Evaluation of Antibiotic Use in Pediatric Patients with Urinary Tract Infections at Ir. Soekarno General Hospital, Sukoharjo, in 2025

Zahro Lailatus Sa'adah; Vivin Marwiyati Rohmana; Bangkit Riska Permata

doi:10.55227/ijhet.v4i4.393

Authors

Zahro Lailatus Sa'adah Duta Bangsa University
Vivin Marwiyati Rohmana
Bangkit Riska Permata Duta Bangsa University

DOI:

https://doi.org/10.55227/ijhet.v4i4.393

Keywords:

Antibiotics, Drug Rationality Evaluation, Urinary Tract Infection, Pediatrics

Abstract

Urinary tract infections (UTIs) are one of the most common bacterial infections in children and require antibiotic therapy. Irrational antibiotic use can lead to resistance, increase costs, and cause side effects. Therefore, evaluation of antibiotic prescribing patterns is necessary to ensure treatment effectiveness and prevent resistance. This study aims to evaluate the rationality of antibiotic use in pediatric patients with UTIs according to management guidelines. This is a descriptive observational study with a retrospective design. The study population was all pediatric inpatients diagnosed with UTI at Ir. Soekarno Sukoharjo Regional General Hospital in 2024. The sample included patient medical records from January to December 2024 who met the inclusion criteria. Evaluation included patient, drug, and dosage accuracy according to national guidelines. Clinical outcomes were assessed based on changes in body temperature at discharge. The results showed that of 61 patients, 42 patients (68.9%) received the correct dose, 47 patients (77%) received the correct drug, and 45 patients (73.5%) received the correct dose. All patients (100%) experienced clinical improvement with normal body temperature at discharge. Most antibiotic prescriptions were in accordance with clinical guidelines. Analysis of the relationship between medication rationality and clinical outcomes showed that medication accuracy was not significantly associated with discharge temperature (p = 0.907). Conversely, dosage accuracy was significantly negatively associated with discharge temperature (r = -0.353; p = 0.005), indicating that appropriate dosing contributed to temperature normalization. Thus, all patients demonstrated improved clinical outcomes.

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