The Effect of Antihypertensive Drugs on Blood Pressure in Preeclamptic Women at RSIA Ananda Makassar in 2020-2022
DOI:
https://doi.org/10.55227/ijhet.v4i4.420Keywords:
Preeclampsia, Antihypertensive Drug, Blood PressureAbstract
Background: The maternal mortality rate (MMR) in Indonesia is still very high, especially maternal mortality where in 2015 the maternal mortality rate (MMR) in Indonesia reached 305 per 100,000 live births caused by bleeding, infection and preeclampsia. This study aims to determine the effect of administering antihypertensive drugs on the blood pressure of preeclamptic mothers at RSIA Ananda Makassar in 2020-2022. Method: Quantitative research with a cross-sectional research design using a total sampling technique, where the number of samples is the same as the population. The samples in this study were mothers diagnosed with preeclampsia at the Ananda Mother and Child Hospital in Makassar, taking into account the inclusion and exclusion criteria. The number of samples in this study was 80 people. Result: Data analysis was carried out univariate and bivariate. Bivariate analysis of the effect of administering antihypertensive drugs on initial and discharge systolic blood pressure using the Wilcoxon test obtained a P-value <0.01 and for initial and discharge diastolic blood pressure a P-value <0.01 was obtained. Changes in decreasing systolic blood pressure using the Mann Whitney test obtained a P-value of <0.01 and diastolic blood pressure obtained a P-value of 0.027 Conclusion: There is an effect of administering antihypertensive drugs on the blood pressure of preeclamptic mothers at RSIA Ananda Makassar in 2020-2022
Downloads
References
Apriyana Ninike. (2021). The Role of Magnesium Sulfate in the Management of Preeclampsia. Journal of Professional Nursing Research, 3(1) 9-16
Awaluddin, A., Mahmud, I., Awaluddin, N., & Indrisari, M. (2021). Profile of Antihypertensive Use in Preeclampsia Patients in General Hospitals. Makassar Health Polytechnic Health Media, XVI(2), 334–342.
Azizah Sitti, Sugijati, Palupi Jenie. (2019). Risks of Full-Dose MgSO4 Administration in Preeclampsia Patients Undergoing Cesarean Section. Malang Journal of Midwifery, 1(1) 39-46
Ferdy, M., Ramadhan, Y., Mulyani, T., & Ariyani, H. (2022). Evaluation of Antihypertensive Drug Use in Inpatients with Preeclampsia at Datu Sanggul Rantau Regional General Hospital (Evaluation of the Use of Antihypertensive Medicines in Inpatient Preeclampsia Patients at Datu Sanggul Rantau Hospital) (Vol. 5, No. 2).
Fitri Amalia, F. (2020). The Effect of Mgso4 Use as a Preventive Therapy for Seizures in Preeclampsia. In Journal of Medical and Health Sciences (Vol. 7, No. 1).
Husna, N., Melinda, C., Sugita, R. D., & Anggraeni, R. (2023). Study of Risk Factors, Treatment Patterns, and Clinical Outcomes of Preeclampsia Patients at Sleman Regional General Hospital, Yogyakarta. Journal of Pharmaceutical & Clinical Sciences, 9(sup), 196
Kundarto, W., & Faizah, R. N. (2021). Evaluation of Antihypertensive Therapy in Patients with Severe Preeclampsia in the Inpatient Unit of Dr. Moewardi General Hospital from January to June 2017. JPSCR: Journal of Pharmaceutical Science and Clinical Research, 6(2), 228.
Kurniawati, D., Septiyono, E. A., & Sari, R. (2020). Preeclampsia and Its Treatment. Journal of Health Science, 100-105
Kusnan, A. (2022). The Effect of Green Tea in Lowering Blood Pressure: A Systematic Review. NURSING UPDATE: Scientific Journal of Nursing P-ISSN: 2085- 5931 e-ISSN: 2623-2871, 13(1), 67-79.
Kusuma, M. A., Setiawati, D., & Haruna, N. (2022). The relationship between preeclampsia and low birth weight (LBW) babies. Jurnal Impresi Indonesia, 1(7), 726–739.
Mustofa, A., Ariningtyas, N. D., Prahasanti, K., & Anas, M. (2021). Relationship Between Maternal Age and Late-Onset Preeclampsia at PKU Muhammadiyah Hospital Surabaya. Herb-Medicine Journal, 4(4), 14.
Noor, Meitria Syahadtina, Santoso, B., Triawanti, Rahardjo, B., Adityawaeman, Harjanto, & Purwanto, B. (2021). The Concept of Preeclampsia: Pathomechanism and Prevention.
Nugroho, H., Meila, O., & Aprilia, S. (2016). The Relationship Between Combination Therapy and the Time to Recovery from Diarrhea in Hospitalized Toddlers at the North Jakarta Regional General Hospital in 2016. Social Clinical Pharmacy Indonesia Journal, 1(2), 84–94.
Nurhayati, S. (2021). Management of Preeclampsia in Pregnant Women. STIKES Ngudia Husada Madura.
Nurmainah, N., Hadad, F. M., & Andrie, M. (2021a). Profile of Proteinuria and Blood Pressure in Patients with Severe Preeclampsia Using Antihypertensive Drugs. Indonesian Journal of Clinical Pharmacy, 10(2), 79.
Putri, D., Mahendra, A. N., Indrayanti, A. W., & Wirata, G. (2020). Profile of nifedipine combined with methyldopa and MgSO4 administration in patients with severe preeclampsia at Mangusada Badung Regional Hospital. Medical Science Abstract, 11(3), 1222–1229.
Rachmaini, F., Juwita, D. A., Abdillah, R., & Rifqi, M. A. (2023). The Effect of Antihypertensive Drug Use on Blood Pressure and Proteinuria in Patients with Severe Preeclampsia at Dr. M. Djamil Hospital. Journal of Pharmaceutical Sciences & Clinical Practice, 9(sup), 175.
Retnaningtyas Erma. (2021). Preeclampsia & Midwifery Care in Preeclampsia (M. K. Retno Palupi Yonni Siwi,.SST (ed.) Strada Press.
Rospia, E. D., Novidaswati, A., & Cahyaningtyas, D. K. (2021). The Relationship Between Parity and Severe Preeclampsia at Panembahan Senopati Bantul Regional General Hospital. Journal Center of Research Publication in Midwifery and Nursing, 5(2), 24–30.
Saddam, M., Saharuddin, S., Yunus, P., Fitriani, R., & Galib, M. (2023). Correlation Analysis between Anxiety and Preeclampsia Incidence in Pregnant Women. UMI Medical Journal, 8(1), 35-45.
Saputri Gusti Rai Saputri. (2020). Evaluation of the Rationality of Antihypertensive Drug Use in Inpatients with Preeclampsia at Jend. Ahmad Yani Metro Regional General Hospital in 2019. Malahayati Pharmacy Journal. 3(2), 139-150
Setiawati, D. (2020). The Role of Inflammation in Pathogenesis of Preeclampsia: An Investigation of interleukin-6, interleukin 10, and the Ratio. International Journal of Medical Reviews and Case Reports, 4(0), 1.
Swastika, W., Kurniawan, A., & Setiawan, H. (2020). Detection and Classification of Car Brands for Billboard Advertising Determination Using Convolution Neural Network. Journal of Information Technology and Computer Science, 7(4), 701.
Ulum, B. (2023). Health Workers' Experiences in Caring for Pregnant Women with Preeclampsia in Jember Regency. Journal of Maternity Nursing Science, 6(1).
Wasilah Tri, Dewi Rasmala. (2022). Evaluation of the Rational Use of Antihypertensive Drugs in Hypertensive Inpatients at H. Hanafie Muara Bungo Regional General Hospital. Journal of Pharmaceutical Education. 2(1), 21-31
Widayani, S. S., Rahmawati, F., & Yasin, N. M. (2022). Comparison of the Effectiveness of Nifedipine and Methyldopa in Controlling Blood Pressure in Patients with Preeclampsia. Pharmaceutical Journal, 18(3),247.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Nurrohmah, Darmawansyih, Dewi Setiawati, Andi Sitti Rahma, Zulfahmi Alwi

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
























