GC-MS Analysis Of Bioactive Compounds From Ethanol Extract Of Yellow Wood Stems (Arcangelisia flava) AS Anti-Inflammatory And Anti-Hyperuricemia

Abstract

Yellow wood (Arcangelisia flava) is a wild plant that can be found in Indonesia although it is not yet widely cultivated. The stems of yellow wood is known to contain various metabolite compounds, including saponins, flavonoids, and tannins. Recent research has found that the flavonoid content in the roots and stemss of yellow wood has xanthine oxidase inhibitory effects that can be used to prevent inflammation and hyperuricemia. This research uses the maceration method, where yellow wood stemss will be made into extract using ethanol as a solvent, and the compound contained in the extract will be analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). The GC-MS analysis result showed that the ethanol extract of yellow wood stemss contain 2-(4-tert-butylphenyl)cyclopropanecarboxylic acid (isomer 2); Tetracyclo [5.2.1.0(2,6).0(3,5)] decane, 4,4-dimethyl; Olean-12-en-28-oic acid, 3-hydroxy-, methyl ester (3 beta); 9-octadecenoic acid, methyl ester, (E); and hexadecanoic acid, methyl ester. These compounds have benefit as anti-inflammatory and antihyperuricemic agent, which can serve as advantageous medicinal ingredient for humans. The result of analysis in the yellow wood stems can serve as a reference for further research to develop the potential of yellow wood stemss leading to traditional medicine.