Literature Review: The Effectiveness Of Brown Rice Diet As Nonpharmacological Nutritional Therapy In Type 2 Diabetes Mellitus Patients

Andi Nur Azizah Alifuddin; Hasan Hasan; Pratiwi Nasir Hamzah

doi:10.55227/ijhet.v4i6.618

Authors

Andi Nur Azizah Alifuddin Universitas Muslim Indonesia
Hasan Hasan Universitas Muslim Indonesia
Pratiwi Nasir Hamzah Universitas Muslim Indonesia

DOI:

https://doi.org/10.55227/ijhet.v4i6.618

Keywords:

Type 2 Diabetes Mellitus, Brown Rice, Non-Pharmacological Nutritional Therapy, Glycemic Control, Glycemic Index.

Abstract

Type 2 diabetes mellitus is a global health problem with a high prevalence in Indonesia and requires comprehensive management, including non-pharmacological nutritional therapy. The choice of carbohydrate sources plays an important role because white rice has a high glycemic index, while brown rice has a lower glycemic index and contains fiber and bioactive compounds that have the potential to help control blood glucose. Therefore, this study aims to determine the nutritional content of brown rice that is relevant to the management of type 2 diabetes, to analyze the effect of brown rice consumption on glycemic control in patients with type 2 diabetes, to determine the effect of a brown rice diet on other metabolic parameters such as body weight, lipid profile, and insulin sensitivity, and to summarize the scientific evidence related to the potential of brown rice as an alternative dietary intervention for patients with type 2 diabetes. This study used a literature review method with a narrative review design. The results of the study showed that brown rice has nutritional content that is relevant to the management of type 2 DM, especially fiber, vitamins, minerals, and bioactive compounds that support improved glucose metabolism. The application of a brown rice diet contributes to improved glycemic control, as indicated by a decrease in fasting blood glucose, postprandial glucose, and HbA1c. In addition, brown rice consumption also has a positive impact on other metabolic parameters, including improved lipid profile, insulin sensitivity, and potential weight control. Overall, brown rice has the potential to be a healthier alternative source of carbohydrates and is applicable as part of non-pharmacological nutritional therapy in patients with type 2 diabetes. It can be concluded that a brown rice diet is an effective and safe non-pharmacological nutritional intervention to support the management of type 2 DM through improved glycemic control and metabolic parameters, making it a recommended alternative carbohydrate source in the patient's diet.

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References

Cahyawardani, C., Sulistyowati, E., & Widajati, E. (2023). Carbohydrate and Fiber Intake on Fasting Blood Glucose Levels in Patients with Type 2 Diabetes Mellitus after Intervention of Brown Rice Diet. Indonesian Journal of Human Nutrition, 10(1), 1–11.

Chaiyakul, S., Ketkham, N., Chaichana, C., Khumkhana, N., Deekum, W., Wongshaya, P., Suwanmalai, T., Hutchinson, C., & Pramyothin, P. (2023). Effects of a novel rice-based diabetes-specific formula on postprandial glucose and gastrointestinal hormones: A double-blinded multi-arm randomized crossover trial. Frontiers in Endocrinology, 14, 1141497.

Clemente-Suárez, V. J., Beltrán-Velasco, A. I., Redondo-Flórez, L., Martín-Rodríguez, A., & Tornero-Aguilera, J. F. (2023). Global impacts of western diet and its effects on metabolism and health: A narrative review. Nutrients, 15(12), 2749.

Du, Q., Fu, R., Zhao, M., & Xu, M. (2025). Comparing a Whole Grain Blend with Polished White Rice for Starch Digestibility and Gut Microbiota Fermentation in Diabetic Patients: An In Vitro Study. Foods, 14(15), 2557.

Federation, I. D. (2013). International diabetes federation: IDF diabetes atlas. Brussels, Belgium.

Haldipur, A. C., & Srividya, N. (2021). Multi-mechanistic in vitro evaluation of antihyperglycemic, antioxidant and antiglycation activities of three phenolic-rich Indian red rice genotypes and in silico evaluation of their phenolic metabolites. Foods, 10(11), 2818.

Handayani, D., Kusumastuty, I., Inayah, A. M., Retnaningtyas, E., Sulistyowati, E., Sasiarini, L., & Rudijanto, A. (2022). Substitution of local Indonesian varieties of brown rice on anthropometry and blood glucose level improvement in type 2 DM patients: a pilot project. Journal of Public Health Research, 11(1), jphr-2021.

Ikeda, N., Yamaguchi, M., & Nishi, N. (2025). Health and economic impacts of increased brown rice consumption on type 2 diabetes in Japan: a simulation study, 2019–2029. Nutrients, 17(3), 532.

Indonesia, P. E. (2021). Pedoman pengelolaan dan pencegahan Diabetes melitus Tipe 2 Dewasa di Indonesia. Pb Perkeni, 46.

Jabeen, R., Jan, N., Naseer, B., Sarangi, P. K., Sridhar, K., Dikkala, P. K., Bhaswant, M., Hussain, S. Z., & Inbaraj, B. S. (2024). Development of germinated-brown-rice-based novel functional beverage enriched with γ-aminobutyric acid: Nutritional and bio-functional characterization. Foods, 13(8), 1282.

Kristianto, Y., Sulistyowati, E., & Sofiani, S. D. (2024). Effect of Brown Rice and Oyster Mushrooms Food Formulation on Blood Sugar and Lipid Profiles of Diabetics. Indonesian Journal of Human Nutrition, 11(1), 75–85.

Kusumastuty, I., Handayani, D., Affandy, Y. I. K. D., Attamimi, N., Innayah, A. M., & Puspitasari, D. A. (2021). Kepatuhan Diet Berbasis Beras Coklat terhadap Glukosa Darah dan Lemak Tubuh Pasien Diabetes Mellitus. Indonesian Journal of Human Nutrition, 8(2), 182–194.

Li, Z., Yan, H., Chen, L., Wang, Y., Liang, J., Feng, X., Hui, S., & Wang, K. (2022). Effects of whole grain intake on glycemic control: A meta‐analysis of randomized controlled trials. Journal of Diabetes Investigation, 13(11), 1814–1824.

Lim, M.-J., Barathikannan, K., Jeong, Y.-J., Chelliah, R., Vijayalakshmi, S., Park, S.-J., & Oh, D.-H. (2023). Exploring the impact of fermentation on brown rice: Health benefits and value-added foods—A comprehensive meta-analysis. Fermentation, 10(1), 3.

Mai, T. T., Trang, T. T., & Hai, T. T. (2020). Effectiveness of germinated brown rice on metabolic syndrome: A randomized control trial in Vietnam. AIMS Public Health, 7(1), 33.

Manzoor, A., Pandey, V. K., Dar, A. H., Fayaz, U., Dash, K. K., Shams, R., Ahmad, S., Bashir, I., Fayaz, J., & Singh, P. (2023). Rice bran: Nutritional, phytochemical, and pharmacological profile and its contribution to human health promotion. Food Chemistry Advances, 2, 100296.

Martuti, D., Widyaswara, G., & Sari, A. N. (2023). Pengaruh Diet Beras Coklat (Oryza sativa L) terhadap Kadar Glukosa Darah Warga Desa Mayang Sukoharjo.

Mendoza-Sarmiento, D., Mistades, E. V, & Hill, A. M. (2023). Effect of pigmented rice consumption on cardiometabolic risk factors: A systematic review of randomized controlled trials. Current Nutrition Reports, 12(4), 797–812.

Mitta, J. R., Vanamali, D. R., & Gara, H. K. (2022). Impact of consumption of brown rice on glycaemic and lipid profile in type 2 diabetics. International Journal of Advances in Medicine, 9(6), 722.

Na, G., Zhang, J., Lv, D., Chen, P., Song, X., Cai, F., Zheng, S., Wan, W., & Shan, Y. (2023). Germinated Brown rice enhanced n-3 PUFA metabolism in type 2 diabetes patients: A randomized controlled trial. Clinical Nutrition, 42(4), 579–589.

Nakamura, S., Ikeuchi, T., Araki, A., Kasuga, K., Watanabe, K., Hirayama, M., Ito, M., & Ohtsubo, K. (2022). Possibility for prevention of type 2 diabetes mellitus and dementia using three kinds of brown rice blends after high-pressure treatment. Foods, 11(6), 818.

Novianto, P. D. R., Desreza, N., & Oktaviyana, C. (2026). Pengaruh Motivasi dan Health Locus of Control terhadap Kepatuhan Pengobatan pada Pasien DM Tipe 2: The Influence of Motivation and Health Locus of Control on Treatment Adherence in Patients Type 2 Diabetes Mellitus. Jurnal Keperawatan Bunda Delima, 8(1), 141–148.

Nugroho, F. A., Latif, A. N. H., Utami, R. W., Kusumastuty, I., Cempaka, A. R., & Handayani, D. (2024). Brown rice improves dietary inflammatory index score, fasting blood glucose level and tumour necrosis factor alpha in diabetes mellitus patients. Food Research, 8(6), 68–73.

Park, J., Oh, S.-K., Doo, M., Chung, H.-J., Park, H.-J., & Chun, H. (2023). Effects of consuming heat-treated dodamssal brown rice containing resistant starch on glucose metabolism in humans. Nutrients, 15(10), 2248.

Pereira, C., Lourenço, V. M., Menezes, R., & Brites, C. (2021). Rice compounds with impact on diabetes control. Foods, 10(9), 1992.

Permatasari, D. I., Sutjiati, E., & Sulistyowati, E. (2023). Effect of brown rice intervention on BMI and waist circumference in patients with type 2 diabetes mellitus. Indonesian Journal of Human Nutrition, 10(1), 77–87.

Rahim, A. F. A., Norhayati, M. N., & Zainudin, A. M. (2021). The effect of a brown-rice diets on glycemic control and metabolic parameters in prediabetes and type 2 diabetes mellitus: a meta-analysis of randomized controlled trials and controlled clinical trials. PeerJ, 9, e11291.

Ren, C., Hong, B., Zhang, S., Yuan, D., Feng, J., Shan, S., Zhang, J., Guan, L., Zhu, L., & Lu, S. (2024). Autoclaving-treated germinated brown rice relieves hyperlipidemia by modulating gut microbiota in humans. Frontiers in Nutrition, 11, 1403200.

Sanders, L. M., Zhu, Y., Wilcox, M. L., Koecher, K., & Maki, K. C. (2023). Whole grain intake, compared to refined grain, improves postprandial glycemia and insulinemia: a systematic review and meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition, 63(21), 5339–5357.

Seckiner, S., Bas, M., Simsir, I. Y., Ozgur, S., Akcay, Y., Aslan, C. G., Kucukerdonmez, O., & Cetinkalp, S. (2024). Effects of dietary carbohydrate concentration and glycemic index on blood glucose variability and free fatty acids in individuals with type 1 diabetes. Nutrients, 16(9), 1383.

Sitanggang, A. B., Joshua, M., Munarko, H., Kusnandar, F., & Budijanto, S. (2021). Increased γ-aminobutyric acid content of germinated brown rice produced in membrane reactor. Food Technology and Biotechnology, 59(3), 295–305.

Susanti, N., Rahayu, S., Mawarni, D., & Sabila, W. (2024). Hubungan pengetahuan, faktor resiko dan tindakan pencegahan diabetes melitus. Healthy Tadulako Journal (Jurnal Kesehatan Tadulako), 10(4), 713–721.

Takano, Y., Kokubun, K., Saika, K., Nishiyama, N., & Taki, Y. (2021). Effect of the intake of brown rice for six months on the cognitive function in healthy elderly persons: A study protocol for a pilot, non-randomized controlled trial. Methods and Protocols, 4(4), 78.

Tantayakhom, S., Inpan, R., Yaja, K., Koonrungsesomboon, N., Teekachunhatean, S., & Na Takuathung, M. (2025). Effects of Rice Bran Supplementation on Metabolic Syndrome-Related Parameters: A Systematic Review and Meta-Analysis. International Journal of Molecular Sciences, 26(18), 9051.

Xu, D., Fu, L., Pan, D., Lu, Y., Yang, C., Wang, Y., Wang, S., & Sun, G. (2021). Role of whole grain consumption in glycaemic control of diabetic patients: a systematic review and meta-analysis of randomized controlled trials. Nutrients, 14(1), 109.

Ying, T., Zheng, J., Kan, J., Li, W., Xue, K., Du, J., Liu, Y., & He, G. (2024). Effects of whole grains on glycemic control: a systematic review and dose-response meta-analysis of prospective cohort studies and randomized controlled trials. Nutrition Journal, 23(1), 47.

Yu, J., Balaji, B., Tinajero, M., Jarvis, S., Khan, T., Vasudevan, S., Ranawana, V., Poobalan, A., Bhupathiraju, S., & Sun, Q. (2022). White rice, brown rice and the risk of type 2 diabetes: A systematic review and meta-analysis. BMJ Open, 12(9), e065426.

Zhao, R., Fajardo, J., & Shen, G. X. (2023). Influence of brown or germinated brown rice supplementation on fecal short-chain fatty acids and microbiome in diet-induced insulin-resistant mice. Microorganisms, 11(11), 2629.