Photobiomodulation Therapy In Enhancing Soft Tissue Healing For Aesthetic Procedures: A Systematic Review

Main Article Content

Asiyah Syaharuddin

Abstract

Photobiomodulation Therapy (PBMT) has emerged as a promising non‑invasive adjunct to accelerate soft tissue healing and improve aesthetic outcomes in cosmetic dental procedures. However, clinical evidence remains heterogeneous, with inconsistent laser parameters and limited comparative data on aesthetic endpoints. This study aimed to evaluate the clinical effectiveness of PBMT in enhancing soft tissue healing and aesthetic outcomes relative to conventional methods in aesthetic dentistry. It employed a systematic review design following the PRISMA 2020 guidelines, using a PICOS framework to search SpringerLink, ScienceDirect, and PubMed for English‑language articles (2020–2025) involving human or animal studies on PBMT and oral soft tissue aesthetics. Seven studies met the inclusion criteria and were analyzed using narrative synthesis without meta‑analysis due to high heterogeneity. Inclusion criteria specified open‑access full‑text articles on gingival contouring, implant surgery, soft tissue grafting, and related procedures, with outcome data on epithelialization, angiogenesis, pain, patient satisfaction, color, and texture. Quality assessment was performed using the Joanna Briggs Institute (JBI) Critical Appraisal Tools. The results show that PBMT consistently improves epithelialization, reduces postoperative pain, enhances tissue color and texture, and increases patient satisfaction, while minimizing hypertrophic scar risk. In conclusion, PBMT accelerates soft tissue healing and aesthetic recovery, though parameter standardization is needed.

Downloads

Download data is not yet available.

Article Details

How to Cite
Asiyah Syaharuddin. (2026). Photobiomodulation Therapy In Enhancing Soft Tissue Healing For Aesthetic Procedures: A Systematic Review . International Journal of Health Engineering and Technology, 5(1). https://doi.org/10.55227/ijhet.v5i1.726
Section
Health

References

Asan, M., Gogineni, S. B., Castelino, R., & Rao, K. (2021). Applications of photobiomodulation therapy in oral medicine—a review. European Journal of Therapeutics, 27(2), 177–178.

Azhibekov, A., Menchisheva, Y., Espolayeva, A., et al. (2024). The efficacy of leukocyte platelet rich fibrin in combination with subepithelial connective tissue graft in peri implant soft tissue augmentation: A randomized controlled clinical trial. Open Journal of Dentistry, 18, e18742106338561.

Bartold, M., & Ivanovski, S. (2025). Biological processes and factors involved in soft and hard tissue healing. Periodontology 2000, 97, 22. https://doi.org/10.1111/prd.12546

Costa Neto, F., Breseghello, I., Paludetto, L. V., et al. (2025). Effect of Er YAG laser bone bed milling with or without photobiomodulation on the bone repair process of additive manufacturing implants in rats. Journal of Photochemistry and Photobiology, 26–27, 100260.

Creswell, J. W., & Creswell, J. D. (2023). Research design: Qualitative, quantitative, and mixed methods approaches (6th ed.). SAGE Publications.

de Abreu, J. M., Nunes, T., Almiro, P. A., Figueiredo, J., & Corte Real, A. (2024). Long term benefits of photobiomodulation therapy on health related quality of life in burning mouth syndrome patients: A prospective study. Journal of Clinical Medicine, 13(14), 4272. https://doi.org/10.3390/jcm13144272

Dompe, D., Moncrieff, L., Matys, J., Grzech Lesniak, K., Kocherova, I., Bryja, A., et al. (2020). Photobiomodulation—underlying mechanism and clinical application. Journal of Clinical Medicine, 9(6), 1724. https://doi.org/10.3390/jcm9061724

Emzir. (2021). Metodologi penelitian pendidikan konsep dan aplikasi. Raja Grafindo Persada.

Mahmoud, E. S., Abd El Baky, A. M., Gouda, O. M., & Hussein, H. G. (2025). Low intensity pulsed ultrasound versus low level laser therapy on peri implant marginal bone preservation and soft tissue healing following dental implant surgery: A randomized controlled trial. Head & Face Medicine, 21, 29.

Pereira, T. C., Martín, J., Kuga, M. C., et al. (2025). Targeted photocatalytic whitening with LED or laser activated hydrogen peroxide gels containing nitrogen doped titanium dioxide: A multistudy clinical analysis of efficacy, sensitivity and energy optimization. Photodiagnosis and Photodynamic Therapy, 55, 104713.

Raja, I. S., Kim, C., Oh, N., Park, J. H., Hong, S. W., Kang, M. S., et al. (2024). Tailoring photobiomodulation to enhance tissue regeneration. Biomaterials, 309, 122623. https://doi.org/10.1016/j.biomaterials.2024.122623

Shenoy, A., Shenoy, N., Avaneendra, T., & Chandra, K. S. (2025). Photobiomodulation: A promising adjunct in periodontal therapy (review). World Academy of Science Journal, 7, 70.

Sudaryono. (2021). Pendekatan kualitatif dalam penelitian edukatif. Depdiknas/Universitas Negeri.

Woo, K. (2024). Photobiomodulation as a multimodal therapy to enhance wound healing and skin regeneration. Medical Lasers, 13(4), 177–182.

Sugiyono. (2022). Metode penelitian kuantitatif, kualitatif, dan R&D (edisi revisi). Alfabeta.

Yaghobee, S., Pourhajibagher, M., Bahrami, R., & Isaabadi, M. (2024). Nano emodin mediated photodynamic therapy for wound healing of donor site after free gingival graft: A parallel clinical trial. Photodiagnosis and Photodynamic Therapy, 45, 103958.