Physical Activity, Sleep Quality, And Gadget Use As Risk Factors For Anemia In Adolescent Girls: A Systematic Literature Review
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Abstract
Anemia among adolescent girls remains a significant public health problem because it can adversely affect growth, learning capacity, productivity, and future reproductive health. In addition to nutritional factors, modern lifestyle changes—including physical activity, sleep quality, and gadget use—are increasingly recognized as potential contributors to anemia risk. This study aimed to synthesize scientific evidence regarding the association of physical activity, sleep quality, and gadget use with anemia among adolescent girls. This study aimed to analyze and synthesize scientific evidence regarding the association of physical activity, sleep quality, and gadget use with anemia among adolescent girls and to identify the underlying mechanisms linking these factors to anemia. This study employed a Systematic Literature Review (SLR) following the PRISMA 2020 guidelines. Literature searches were conducted in the PubMed, Scopus, ScienceDirect, ProQuest, Google Scholar, and Garuda databases for articles published between 2020 and 2025. Studies were selected based on predefined inclusion and exclusion criteria, assessed for methodological quality, and analyzed using narrative synthesis and thematic analysis. A total of 25 articles met the eligibility criteria and were included in the final synthesis. The review findings indicated that unbalanced physical activity, poor sleep quality, and excessive gadget use were associated with an increased risk of anemia among adolescent girls. Both insufficient and excessive physical activity without adequate nutritional support may affect hemoglobin levels. Poor sleep quality was linked to impaired iron metabolism and hemoglobin synthesis, while excessive gadget use indirectly contributed to anemia through increased screen time, sedentary behavior, and reduced sleep quality. These findings suggest that these three lifestyle factors interact and collectively influence the risk of anemia. In conclusion, preventing anemia among adolescent girls requires a comprehensive approach that addresses not only nutritional factors but also healthy physical activity, adequate sleep, and responsible gadget use. The findings provide evidence for developing adolescent health programs and future research on lifestyle determinants of anemia.
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References
Agustina, R., Wirawan, F., Sadariskar, A. A., Setianingsing, A. A., Nadiya, K., Prafiantini, E., Asri, E. K., Purwanti, T. S., Kusyuniati, S., Karyadi, E., & Raut, M. K. (2021). Associations of Knowledge, Attitudes, and Practices Toward Anemia with Anemia Prevalence and Height-for-Age Z-Score Among Indonesian Adolescent Girls. Food and Nutrition Bulletin, 42 (1_suppl), S92–S108. https://doi.org/10.1177/03795721211011136
Anwar, S., Rauf, M. K., Farooq, M., Khan, M., Maqsood, W., & Gulraiz, S. (2025). Iron Deficiency Anemia in Teenage Girls: The Impact of Menarche and Nutritional Care. Cureus, 17 (5), 1–9. https://doi.org/10.7759/cureus.84997
Asrullah, M., Maula, A. W., Frans, S. O., Dewi, S. L., L’Hoir, M., Feskens, E. J. M., & Melse-Boonstra, A. (2025). Sleep Quality, Depression, and the Risk of Anemia in Adolescents Aged 10–19 Years During One Year of the COVID-19 Pandemic in Indonesia. Stress and Health, 41 (3), 1–13. https://doi.org/10.1002/smi.70046
Aura, A., Sormunen, M., & Tossavainen, K. (2016). The relation of socio-ecological factors to adolescents’ health-related behavior: A literature review. Health Education, 116 (2), 177–201. https://doi.org/10.1108/HE-03-2014-0029
Briggs, J. (2019). System for the Unified Management, Assessment, and Review of Information (SUMARI). Journal of the Medical Library Association, 107 (4). https://doi.org/10.1177/10483950211008345b
Dyah Krisnawati Satia Pratiwi, Anastya, E., & Nahdiyah Karimah. (2024). Anemia and Sleep Patterns Among Adolescent Women in Surakarta City. Journal for Quality in Women’s Health, 7 (2), 121–125. https://doi.org/10.30994/jqwh.v7i2.234
Fitri, N. L., Sudaryanti, L., & Amalia, R. B. (2024). The relationship between nutrition, physical activity, and sleep quality and changes in anemia status among adolescent girls with anemia. World Journal of Advanced Research and Reviews, 24(02), 990–995.
Grootendorst, S., de Wilde, J., van Dooijeweert, B., van Vuren, A., van Solinge, W., Schutgens, R., van Wijk, R., & Bartels, M. (2021). The interplay between drivers of erythropoiesis and iron homeostasis in rare hereditary anemias: Tipping the balance. International Journal of Molecular Sciences, 22 (4), 1–17. https://doi.org/10.3390/ijms22042204
Hanif, A. S., & Margawati, A. (2026). Association of iron and nutritional status with sleep quality in adolescent girls: A cross-sectional study. Abstract. 11(1), 125–132.
He, X., Pan, B., Ma, N., Li, D., Kong, W., Liu, Q., Liu, X., Wang, X., Deng, X., & Yang, K. (2025). The association of screen time and the risk of sleep outcomes: a systematic review and meta-analysis. Frontiers in Psychiatry, 16 (December). https://doi.org/10.3389/fpsyt.2025.1640263
Idahafni, Nurjanah, Aramico, B., Abdullah, A., & Zahara, M. (2025). The Relationship Between Gadget Addiction and Body Mass Index and Anemia in Teenage Girls. Indonesian Journal of Global Health Research, 7 (6), 649–656. https://doi.org/10.37287/ijghr.v2i4.250
Jiao, Y., Butoyi, C., Zhang, Q., Intchasso Adotey, S. A. A., Chen, M., Shen, W., Wang, D., Yuan, G., & Jia, J. (2025). Sleep disorders impact hormonal regulation: unravelling the relationship among sleep disorders, hormones, and metabolic diseases. Diabetology and Metabolic Syndrome, 17 (1). https://doi.org/10.1186/s13098-025-01871-w
Indonesian Ministry of Health. (2023). Indonesian Health Survey (SKI) 2023. In Indonesian Ministry of Health.
Knijff, M., Roshita, A., Suryantan, J., Izwardy, D., & Rah, J. H. (2021). Frequent Consumption of Micronutrient-Rich Foods Is Associated With Reduced Risk of Anemia Among Adolescent Girls and Boys in Indonesia: A Cross-Sectional Study. Food and Nutrition Bulletin, 42 (1_suppl), S59–S71. https://doi.org/10.1177/0379572120977455
Maghfirah, N., Masfufah Masfufah, & Nuristha Febrianti. (2024). Screen Time and Sleep Quality in Relation to Hemoglobin Levels in Adolescent Girls. Vitamin: Journal of General Health Sciences, 3 (1), 01–09. https://doi.org/10.61132/vitamin.v3i1.730
Mustakin, S. R., & Adam, A. (2026). Association Between Nutritional Status and Anemia Incidence Among High School Adolescent Girls. 5, 208–218.
Nguyen, A. D., Costa, P. C., & Raizen, D. M. (2024). A perfect storm: sleep loss causes systemic inflammation and death. Cell Research, 34 (5), 341–342. https://doi.org/10.1038/s41422-023-00924-x
Ocktariyana, Flora, R., Eka, Y. M., Zulkarnain, & Lasepha, A. (2024). Risk Factors for Iron Deficiency Anemia Among Adolescents in Developing Countries: A Literature Review. Indonesian Journal of Global Health Research, 6 (3), 1343–1354. https://doi.org/10.37287/ijghr.v2i4.250
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., Chou, R., Glanville, J., Grimshaw, J. M., Hróbjartsson, A., Lalu, M. M., Li, T., Loder, E. W., Mayo-Wilson, E., McDonald, S., … Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372 . https://doi.org/10.1136/bmj.n71
Patrisia, S., Artawan, I. M., Buntoro, I. F., & Woda, R. R. (2025). Relationship of Physical Activity with the Incidence of Anemia in Junior High School Adolescent Girls in Kupang City. East African Scholars Journal of Medical Sciences, 8 (05), 147–152. https://doi.org/10.36349/easms.2025.v08i05.002
Pibriyanti, K., Safitri, D. I. I., Damayanti, A. Y., Mufidah, I., Luthfiya, L., & Arifah, D. A. (2025). Correlation of Sleep Quality and Diet Quality with Hemoglobin Levels in Adolescent Girls. *Amerta Nutrition*, 9 (3), 486–495. https://doi.org/10.20473/amnt.v9i3.2025.486-495
Rahmatina, A. N., Ghozali, M., Adnani, Q. E., Hilmanto, D., Zuhairini, Y., Susiarno, H., & Panigoro, R. (2025). A Scoping Review of Nutritional Intake and Physical Activity in Adolescent Girls with Anemia. International Journal of Women’s Health, 17 (August), 2891–2907.
Ricketts, E. J., Joyce, D. S., Rissman, A. J., Burgess, H. J., Colwell, C. S., Lack, L. C., & Gradisar, M. (2022). Electric lighting, adolescent sleep and circadian outcomes, and recommendations for improving light health. Sleep Medicine Reviews, 64 (310). https://doi.org/10.1016/j.smrv.2022.101667
Rogers, E. M., Banks, N. F., & Jenkins, N. D. M. (2024). The effects of sleep disruption on metabolism, hunger, and satiety, and the influence of psychosocial stress and exercise: A narrative review. Diabetes/Metabolism Research and Reviews, 40 (2). https://doi.org/10.1002/dmrr.3667
Rzanny, P., & Ochodek, M. (2025). A Systematic Literature Review of Inter-Commit Fine-Grained Source Code Changes: Assessing Readiness for Large-Scale Data Collection. ACM Computing Surveys, 58 (4). https://doi.org/10.1145/3767321
Sahashika, A. P., & Setiyaningrum, Z. (2024). The Relationship Between Sleep Quality and the Incidence of Anemia Among Adolescent Girls at SMK Batik 2 Surakarta. Jurnal Ilmiah Universitas Batanghari Jambi, 24 (3), 2164. https://doi.org/10.33087/jiubj.v24i3.5687
Sari, P., Herawati, D. M. D., Dhamayanti, M., & Hilmanto, D. (2022). Anemia among Adolescent Girls in West Java, Indonesia: Related Factors and Consequences on Quality of Life. Nutrients, 14 (18), 1–13. https://doi.org/10.3390/nu14183777
Sharief, S. A., & Hamang, S. H. (2026). Gadget Use Duration, Sleep Quality, and Anemia Among Adolescent Girls: A Cross-Sectional Study in Makassar, Indonesia. 6 (1), 30–41. https://doi.org/10.47650/pjphsr.v6i1.2463
Vorster, A. P. A., W., van S. J., Pack, A. I., Huber, R., & Schmidt, M. H. (2024). Sleep Health. Clinical and Translational Neuroscience, 3 (8), 1–15. https://doi.org/10.1056/EVIDra2300269
Votsi, I. C., & Koutelidakis, A. (2025). How Screen Time Affects Greek Schoolchildren’s Eating Habits and Functional Food Consumption?—A Cross-Sectional Study. Nutrients, 17 (8). https://doi.org/10.3390/nu17081311
WHO. (2025). Prevalence of anemia in women of reproductive age. The Global Health Observatory, 49.
Yaumil Fauziah, Nukhbatul Bidayati Haka, & Mega Octamelia. (2025). Anemia Incidence in Adolescent Girls. Bulletin of Inspiring Developments and Achievements in Midwifery, 1 (1), 22–31. https://doi.org/10.69855/bidan.v1i1.73