Evaluation Of The Antioxidant Activity Of Lotion Containing Ethanolic Extract Of Matoa Leaves (Pometia Pinnata J.R.Forst, & G.Forst.)

Mei Vita Rachma Pertiwi; Anna Fitriawati; Annie Rahmatillah

doi:10.55227/ijhet.v4i6.672

Authors

Mei Vita Rachma Pertiwi Universitas Duta Bangsa Surakarta
Anna Fitriawati Universitas Duta Bangsa Surakarta
Annie Rahmatillah Universitas Duta Bangsa Surakarta

DOI:

https://doi.org/10.55227/ijhet.v4i6.672

Keywords:

Antioxidant Activity, DPPH, Ethanol Extract, Lotion Formulation, Pometia Pinnata

Abstract

Skin exposure to environmental stress produces free radicals and ROS that accelerate aging and skin damage, while antioxidant Lotions from natural extracts such as Matoa leaves (Pometia pinnata) offer protection. This experimental study aimed to evaluate the antioxidant activity of ethanol extracts, the effect of concentration (0.5-6%) on the physical quality of Lotions, and the DPPH scavenging ability of the final Lotion. The population of all Matoa leaf extract Lotion formulations; a sample of 2 kg of fresh leaves from Matesih, Karanganyar was purposively selected. Instruments included a UV-Vis spectrophotometer (517 nm), a Brookfield viscometer, a pH meter; SPSS 28.0 was analyzed by ANOVA, regression for IC50. The extract was very potent (IC50 43.07 ppm) containing flavonoids, alkaloids, saponins, tannins; All Lotions met the standards (homogeneous, pH 5.22-6.34, viscosity 10,100-12,740 cP, spreadability 5-6.5 cm), FV (6%) was optimal (IC50 66.30 ppm, strong). High concentrations increased inhibition but increased viscosity, decreased spreadability (p<0.05). The findings confirm that Matoa Lotion is effective for herbal skin care; further in vivo and stability testing is recommended.

Downloads

Download data is not yet available.

References

Abriyani, E., Fikayuniar, L., & Safitri, F. (2021). Phytochemical screening and antioxidant bioactivity of methanol extract of Ipomoea carnea Jack. flowers using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Pharma Xplore, 6(1).

Achmad, SA, & Syamsul, K. (2022). Standardization of herbal leaf simplicia for extraction. Indonesian Pharmaceutical Journal, 18(2), 45-52.

Alkogajeva, G., Rahmatillah, A., & Luthfiyanti, N. (2025). Evaluation of the antioxidant potential of a combination toner made from Cosmos caudatus Kunth and aloe vera. Pharmasipha: Pharmaceutical Journal of Islamic Pharmacy, 9(2).https://doi.org/10.21111/pharmasipha.v9i2

Ambarsari, N., & Dayanti, R. (2024). Literature review: Antioxidant activity of extracts and fractions of Matoa (Pometia pinnata) leaves. Journal of Syifa Sciences and Clinical Research, 5(3).https://doi.org/10.37311/jsscr.v5i3.24251

Aprilliani, A., Supriyanta, J., & Badriah, L. (2022). Formulation and effectiveness test of antioxidant handbody Lotion from 70% ethanol extract of cucumber (Cucumis sativus L.) using the DPPH method. Farmagazine Journal, 9(1), 20.https://doi.org/10.47653/farm.v9i1.596

Asari, YD, Nur'Aini, L., Ikmalanas, S., & Paramita, V. (2024). Effectiveness of triethanolamine as emulsifier in chamomile Lotion stability. Journal of Vocational Studies on Applied Research, 6(1), 17–20.https://doi.org/10.14710/jvsar.v6i1.23712

Ayu Putu Widiasriani, I., Udayani, NNW, Putri Triansyah, GA, Mahita Kumari Dewi, NPE, Eva Wulandari, NLW, & Sri Prabandari, AAS (2024). Review article: The role of flavonoid antioxidants in inhibiting free radicals. Journal of Syifa Sciences and Clinical Research, 6(2).https://doi.org/10.37311/jsscr.v6i2.27055

Creswell, J. W., & Creswell, J. D. (2022). Research design: Qualitative, quantitative, and mixed methods approaches (6th ed.). SAGE Publications.https://doi.org/10.4135/9781071817978

Emzir. (2021). Quantitative research methods. Pustaka Setia.

Fadhila, N., Dewaanti, A., & Syarif, D. (2022). Determination of specific and non-specific parameters of watermelon rind extract. Indonesian Pharmaceutical Human Journal, 5(1), 159–166.https://doi.org/10.36387/jifi.v5i1.857

Ginting, S., Sianipar, MP, Charissa, J., & Mardiana, N. (2025). Determination of flavonoid content of Matoa (Pometia pinnata) leaf extract using UV-Vis spectrophotometry method. Jurnal Deli Medical and Health Science, 2.http://ejournal.delihusada.ac.id/index.php/JDMHC

Hanafi, IC, Sirait, SM, Sulistiawaty, L., & Setyawati, SR (2020). Toxicity test with BSLT method on methanol, ethyl acetate extract, hexane on seeds and rind of Matoa extract (Pometia pinnata). Oriental Journal of Chemistry, 36(6), 1143–1147.https://doi.org/10.13005/ojc/360618

Ika Julianti Tambunan, & Siti Muliani. (2025). Formulation and antioxidant activity test of body Lotion preparation of ethanol extract of sky mustard leaves (Cyanthillium cinereum (L) H.Rob) as a moisturizer. JOURNAL OF FARMASIMED (JFM), 7(2), 187–194.https://doi.org/10.35451/jfm.v7i2.2441

Islami, D., Anggraini, L., & Wardaniati, I.